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Accelerated growth in the absence of DNA replication origins

Author

Listed:
  • Michelle Hawkins

    (School of Biology, University of Nottingham, Queen’s Medical Centre, Nottingham NG7 2UH, UK)

  • Sunir Malla

    (Deep Seq, University of Nottingham, Queen’s Medical Centre, Nottingham NG7 2UH, UK)

  • Martin J. Blythe

    (Deep Seq, University of Nottingham, Queen’s Medical Centre, Nottingham NG7 2UH, UK)

  • Conrad A. Nieduszynski

    (School of Biology, University of Nottingham, Queen’s Medical Centre, Nottingham NG7 2UH, UK)

  • Thorsten Allers

    (School of Biology, University of Nottingham, Queen’s Medical Centre, Nottingham NG7 2UH, UK)

Abstract

When all origins of replication are deleted from the archaeon Haloferax volcanii, homologous recombination is used to initiate DNA replication and the growth rate is accelerated.

Suggested Citation

  • Michelle Hawkins & Sunir Malla & Martin J. Blythe & Conrad A. Nieduszynski & Thorsten Allers, 2013. "Accelerated growth in the absence of DNA replication origins," Nature, Nature, vol. 503(7477), pages 544-547, November.
    • Handle: RePEc:nat:nature:v:503:y:2013:i:7477:d:10.1038_nature12650
    DOI: 10.1038/nature12650
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    Cited by:

    1. Dayana E. Salas-Leiva & Eelco C. Tromer & Bruce A. Curtis & Jon Jerlström-Hultqvist & Martin Kolisko & Zhenzhen Yi & Joan S. Salas-Leiva & Lucie Gallot-Lavallée & Shelby K. Williams & Geert J. P. L. K, 2021. "Genomic analysis finds no evidence of canonical eukaryotic DNA processing complexes in a free-living protist," Nature Communications, Nature, vol. 12(1), pages 1-13, December.

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