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Staphylococcus δ-toxin induces allergic skin disease by activating mast cells

Author

Listed:
  • Yuumi Nakamura

    (University of Michigan Medical School)

  • Jon Oscherwitz

    (University of Michigan Medical School
    VA Ann Arbor Healthcare System, 2215 Fuller Road)

  • Kemp B. Cease

    (University of Michigan Medical School
    VA Ann Arbor Healthcare System, 2215 Fuller Road)

  • Susana M. Chan

    (University of Michigan Medical School)

  • Raul Muñoz-Planillo

    (University of Michigan Medical School)

  • Mizuho Hasegawa

    (University of Michigan Medical School)

  • Amer E. Villaruz

    (Laboratory of Human Bacterial Pathogenesis, National Institute of Allergy and Infectious Diseases, US National Institutes of Health)

  • Gordon Y. C. Cheung

    (Laboratory of Human Bacterial Pathogenesis, National Institute of Allergy and Infectious Diseases, US National Institutes of Health)

  • Martin J. McGavin

    (and Centre for Human Immunology, Western University, University of Western Ontario, London, Ontario, N6A 5C1, Canada)

  • Jeffrey B. Travers

    (Indiana University School of Medicine)

  • Michael Otto

    (Laboratory of Human Bacterial Pathogenesis, National Institute of Allergy and Infectious Diseases, US National Institutes of Health)

  • Naohiro Inohara

    (University of Michigan Medical School)

  • Gabriel Núñez

    (University of Michigan Medical School)

Abstract

Staphylococcus aureus δ-toxin is an inducer of mast cell degranulation in mice and is important for promoting inflammatory skin disease.

Suggested Citation

  • Yuumi Nakamura & Jon Oscherwitz & Kemp B. Cease & Susana M. Chan & Raul Muñoz-Planillo & Mizuho Hasegawa & Amer E. Villaruz & Gordon Y. C. Cheung & Martin J. McGavin & Jeffrey B. Travers & Michael Ott, 2013. "Staphylococcus δ-toxin induces allergic skin disease by activating mast cells," Nature, Nature, vol. 503(7476), pages 397-401, November.
    • Handle: RePEc:nat:nature:v:503:y:2013:i:7476:d:10.1038_nature12655
    DOI: 10.1038/nature12655
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    Cited by:

    1. Yuriko Yamazaki & Tomoka Ito & Seitaro Nakagawa & Takashi Sugihira & Chinami Kurita-Tachibana & Amer E. Villaruz & Kensuke Ishiguro & Barbora Salcman & Shuo Li & Sanami Takada & Naohiro Inohara & Yoko, 2024. "Altered genomic methylation promotes Staphylococcus aureus persistence in hospital environment," Nature Communications, Nature, vol. 15(1), pages 1-15, December.

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