IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v500y2013i7464d10.1038_nature12451.html
   My bibliography  Save this article

lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs

Author

Listed:
  • Liuqing Yang

    (Howard Hughes Medical Institute, University of California San Diego
    The University of Texas MD Anderson Cancer Center)

  • Chunru Lin

    (Howard Hughes Medical Institute, University of California San Diego
    The University of Texas MD Anderson Cancer Center)

  • Chunyu Jin

    (Howard Hughes Medical Institute, University of California San Diego)

  • Joy C. Yang

    (School of Medicine, University of California Davis)

  • Bogdan Tanasa

    (Howard Hughes Medical Institute, University of California San Diego
    Graduate Program, Kellogg School of Science and Technology, The Scripps Research Institute)

  • Wenbo Li

    (Howard Hughes Medical Institute, University of California San Diego)

  • Daria Merkurjev

    (Howard Hughes Medical Institute, University of California San Diego
    Bioinformatics and System Biology Program, University of California San Diego)

  • Kenneth A. Ohgi

    (Howard Hughes Medical Institute, University of California San Diego)

  • Da Meng

    (Neurosciences Graduate Program, University of California San Diego)

  • Jie Zhang

    (Howard Hughes Medical Institute, University of California San Diego)

  • Christopher P. Evans

    (School of Medicine, University of California Davis)

  • Michael G. Rosenfeld

    (Howard Hughes Medical Institute, University of California San Diego)

Abstract

A study of prostate cancer cells reveals a transcriptional activation role for long non-coding RNAs (PRNCR1 and PCGEM1) that bind to the androgen receptor, and is also observed for the truncated androgen receptor characteristic of many aggressive prostate cancers.

Suggested Citation

  • Liuqing Yang & Chunru Lin & Chunyu Jin & Joy C. Yang & Bogdan Tanasa & Wenbo Li & Daria Merkurjev & Kenneth A. Ohgi & Da Meng & Jie Zhang & Christopher P. Evans & Michael G. Rosenfeld, 2013. "lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs," Nature, Nature, vol. 500(7464), pages 598-602, August.
    • Handle: RePEc:nat:nature:v:500:y:2013:i:7464:d:10.1038_nature12451
    DOI: 10.1038/nature12451
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature12451
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature12451?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:500:y:2013:i:7464:d:10.1038_nature12451. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.