IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v500y2013i7460d10.1038_nature12302.html
   My bibliography  Save this article

Unusual base pairing during the decoding of a stop codon by the ribosome

Author

Listed:
  • Israel S. Fernández

    (MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK)

  • Chyan Leong Ng

    (MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK
    Present address: Institute of Systems Biology, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia.)

  • Ann C. Kelley

    (MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK)

  • Guowei Wu

    (University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, New York 14642, USA)

  • Yi-Tao Yu

    (University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, New York 14642, USA)

  • V. Ramakrishnan

    (MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK)

Abstract

Here, the structure of the 30S ribosomal subunit and the 70S ribosome in complex with a messenger RNA with pseudouridine in the place of uridine reveals unexpected base pairing.

Suggested Citation

  • Israel S. Fernández & Chyan Leong Ng & Ann C. Kelley & Guowei Wu & Yi-Tao Yu & V. Ramakrishnan, 2013. "Unusual base pairing during the decoding of a stop codon by the ribosome," Nature, Nature, vol. 500(7460), pages 107-110, August.
    • Handle: RePEc:nat:nature:v:500:y:2013:i:7460:d:10.1038_nature12302
    DOI: 10.1038/nature12302
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature12302
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature12302?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:500:y:2013:i:7460:d:10.1038_nature12302. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.