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Metal-free oxidation of aromatic carbon–hydrogen bonds through a reverse-rebound mechanism

Author

Listed:
  • Changxia Yuan

    (University of Texas at Austin)

  • Yong Liang

    (University of California)

  • Taylor Hernandez

    (University of Texas at Austin)

  • Adrian Berriochoa

    (University of Texas at Austin)

  • Kendall N. Houk

    (University of California)

  • Dionicio Siegel

    (University of Texas at Austin)

Abstract

Phthaloyl peroxide functions as a selective oxidant of C–H bonds in the transformation of arenes to phenols under mild conditions, in a reaction that is compatible with a wide array of functional groups.

Suggested Citation

  • Changxia Yuan & Yong Liang & Taylor Hernandez & Adrian Berriochoa & Kendall N. Houk & Dionicio Siegel, 2013. "Metal-free oxidation of aromatic carbon–hydrogen bonds through a reverse-rebound mechanism," Nature, Nature, vol. 499(7457), pages 192-196, July.
  • Handle: RePEc:nat:nature:v:499:y:2013:i:7457:d:10.1038_nature12284
    DOI: 10.1038/nature12284
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    Cited by:

    1. Hao Long & Tian-Sheng Chen & Jinshuai Song & Shaobin Zhu & Hai-Chao Xu, 2022. "Electrochemical aromatic C–H hydroxylation in continuous flow," Nature Communications, Nature, vol. 13(1), pages 1-7, December.

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