Author
Listed:
- James O’Malley
(MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh EH16 4UU, UK)
- Stavroula Skylaki
(Stem Cell Dynamics Research Unit, Helmholtz Center Munich, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany)
- Kumiko A. Iwabuchi
(MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh EH16 4UU, UK)
- Eleni Chantzoura
(MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh EH16 4UU, UK)
- Tyson Ruetz
(MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh EH16 4UU, UK)
- Anna Johnsson
(Laboratory for Molecular Neurobiology, Karolinska Institute, Scheeles väg 1, SE-171 77 Stockholm, Sweden)
- Simon R. Tomlinson
(MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh EH16 4UU, UK)
- Sten Linnarsson
(Laboratory for Molecular Neurobiology, Karolinska Institute, Scheeles väg 1, SE-171 77 Stockholm, Sweden)
- Keisuke Kaji
(MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh BioQuarter, 5 Little France Drive, Edinburgh EH16 4UU, UK)
Abstract
Cellular reprogramming is shown to occur in an ordered, stepwise manner, marked by changes in the cell-surface markers CD44, ICAM1 and Nanog–eGFP; molecular characterization of discrete subpopulations of partially reprogrammed cells shows that reprogramming is not simply the reversal of the normal development process.
Suggested Citation
James O’Malley & Stavroula Skylaki & Kumiko A. Iwabuchi & Eleni Chantzoura & Tyson Ruetz & Anna Johnsson & Simon R. Tomlinson & Sten Linnarsson & Keisuke Kaji, 2013.
"High-resolution analysis with novel cell-surface markers identifies routes to iPS cells,"
Nature, Nature, vol. 499(7456), pages 88-91, July.
Handle:
RePEc:nat:nature:v:499:y:2013:i:7456:d:10.1038_nature12243
DOI: 10.1038/nature12243
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