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Meis1 regulates postnatal cardiomyocyte cell cycle arrest

Author

Listed:
  • Ahmed I. Mahmoud

    (The University of Texas Southwestern Medical Center)

  • Fatih Kocabas

    (The University of Texas Southwestern Medical Center)

  • Shalini A. Muralidhar

    (The University of Texas Southwestern Medical Center)

  • Wataru Kimura

    (The University of Texas Southwestern Medical Center)

  • Ahmed S. Koura

    (School of Medicine, Ain Shams University)

  • Suwannee Thet

    (The University of Texas Southwestern Medical Center)

  • Enzo R. Porrello

    (School of Biomedical Sciences, The University of Queensland)

  • Hesham A. Sadek

    (The University of Texas Southwestern Medical Center)

Abstract

The neonatal heart has a high regenerative capacity that is lost in adult life; the transcription factor Meis1 has been identified as a relevant proliferative switch for this transition, providing a potential therapeutic target for adult heart regeneration.

Suggested Citation

  • Ahmed I. Mahmoud & Fatih Kocabas & Shalini A. Muralidhar & Wataru Kimura & Ahmed S. Koura & Suwannee Thet & Enzo R. Porrello & Hesham A. Sadek, 2013. "Meis1 regulates postnatal cardiomyocyte cell cycle arrest," Nature, Nature, vol. 497(7448), pages 249-253, May.
    • Handle: RePEc:nat:nature:v:497:y:2013:i:7448:d:10.1038_nature12054
    DOI: 10.1038/nature12054
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    Cited by:

    1. Ian Fernandes & Shunsuke Funakoshi & Homaira Hamidzada & Slava Epelman & Gordon Keller, 2023. "Modeling cardiac fibroblast heterogeneity from human pluripotent stem cell-derived epicardial cells," Nature Communications, Nature, vol. 14(1), pages 1-19, December.
    2. Yinuo Wang & Adel Elsherbiny & Linda Kessler & Julio Cordero & Haojie Shi & Heike Serke & Olga Lityagina & Felix A. Trogisch & Mona Malek Mohammadi & Ibrahim El-Battrawy & Johannes Backs & Thomas Wiel, 2022. "Lamin A/C-dependent chromatin architecture safeguards naïve pluripotency to prevent aberrant cardiovascular cell fate and function," Nature Communications, Nature, vol. 13(1), pages 1-24, December.
    3. Xiaohai Zhou & Chenyang Zhang & Xueying Wu & Xinli Hu & Yan Zhang & Xuelian Wang & Lixia Zheng & Peng Gao & Jianyong Du & Wen Zheng & Haibao Shang & Keping Hu & Zhengfan Jiang & Yu Nie & Shengshou Hu , 2022. "Dusp6 deficiency attenuates neutrophil-mediated cardiac damage in the acute inflammatory phase of myocardial infarction," Nature Communications, Nature, vol. 13(1), pages 1-19, December.

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