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Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1

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Listed:
  • A. Marijke Keestra

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Maria G. Winter

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Josef J. Auburger

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Simon P. Fräßle

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Mariana N. Xavier

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Sebastian E. Winter

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Anita Kim

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Victor Poon

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Mariëtta M. Ravesloot

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Julian F. T. Waldenmaier

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Renée M. Tsolis

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Richard A. Eigenheer

    (Proteomics Core Facility, UC Davis Genome Center, University of California at Davis)

  • Andreas J. Bäumler

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

Abstract

Salmonella effector proteins trigger host innate immunity through the activation of small Rho GTPases, which, in turn, is sensed by the NOD1/2 signalling pathway.

Suggested Citation

  • A. Marijke Keestra & Maria G. Winter & Josef J. Auburger & Simon P. Fräßle & Mariana N. Xavier & Sebastian E. Winter & Anita Kim & Victor Poon & Mariëtta M. Ravesloot & Julian F. T. Waldenmaier & René, 2013. "Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1," Nature, Nature, vol. 496(7444), pages 233-237, April.
    • Handle: RePEc:nat:nature:v:496:y:2013:i:7444:d:10.1038_nature12025
    DOI: 10.1038/nature12025
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    Cited by:

    1. Xiaoyi Cheng & Radwa Barakat & Giulia Pavani & Masuma Khatun Usha & Rodolfo Calderon & Elizabeth Snella & Abigail Gorden & Yudi Zhang & Paul Gadue & Deborah L. French & Karin S. Dorman & Antonella Fid, 2023. "Nod1-dependent NF-kB activation initiates hematopoietic stem cell specification in response to small Rho GTPases," Nature Communications, Nature, vol. 14(1), pages 1-19, December.
    2. Christopher von Beek & Anna Fahlgren & Petra Geiser & Maria Letizia Di Martino & Otto Lindahl & Grisna I. Prensa & Erika Mendez-Enriquez & Jens Eriksson & Jenny Hallgren & Maria Fällman & Gunnar Pejle, 2024. "A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
    3. Serena Petracchini & Daniel Hamaoui & Anne Doye & Atef Asnacios & Florian Fage & Elisa Vitiello & Martial Balland & Sebastien Janel & Frank Lafont & Mukund Gupta & Benoit Ladoux & Jerôme Gilleron & Te, 2022. "Optineurin links Hace1-dependent Rac ubiquitylation to integrin-mediated mechanotransduction to control bacterial invasion and cell division," Nature Communications, Nature, vol. 13(1), pages 1-22, December.

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