IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v496y2013i7444d10.1038_nature12025.html
   My bibliography  Save this article

Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1

Author

Listed:
  • A. Marijke Keestra

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Maria G. Winter

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Josef J. Auburger

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Simon P. Fräßle

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Mariana N. Xavier

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Sebastian E. Winter

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Anita Kim

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Victor Poon

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Mariëtta M. Ravesloot

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Julian F. T. Waldenmaier

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Renée M. Tsolis

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

  • Richard A. Eigenheer

    (Proteomics Core Facility, UC Davis Genome Center, University of California at Davis)

  • Andreas J. Bäumler

    (School of Medicine, University of California at Davis, One Shields Avenue, Davis, California 95616, USA)

Abstract

Salmonella effector proteins trigger host innate immunity through the activation of small Rho GTPases, which, in turn, is sensed by the NOD1/2 signalling pathway.

Suggested Citation

  • A. Marijke Keestra & Maria G. Winter & Josef J. Auburger & Simon P. Fräßle & Mariana N. Xavier & Sebastian E. Winter & Anita Kim & Victor Poon & Mariëtta M. Ravesloot & Julian F. T. Waldenmaier & René, 2013. "Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1," Nature, Nature, vol. 496(7444), pages 233-237, April.
    • Handle: RePEc:nat:nature:v:496:y:2013:i:7444:d:10.1038_nature12025
    DOI: 10.1038/nature12025
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature12025
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature12025?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Christopher von Beek & Anna Fahlgren & Petra Geiser & Maria Letizia Di Martino & Otto Lindahl & Grisna I. Prensa & Erika Mendez-Enriquez & Jens Eriksson & Jenny Hallgren & Maria Fällman & Gunnar Pejle, 2024. "A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
    2. Serena Petracchini & Daniel Hamaoui & Anne Doye & Atef Asnacios & Florian Fage & Elisa Vitiello & Martial Balland & Sebastien Janel & Frank Lafont & Mukund Gupta & Benoit Ladoux & Jerôme Gilleron & Te, 2022. "Optineurin links Hace1-dependent Rac ubiquitylation to integrin-mediated mechanotransduction to control bacterial invasion and cell division," Nature Communications, Nature, vol. 13(1), pages 1-22, December.
    3. Xiaoyi Cheng & Radwa Barakat & Giulia Pavani & Masuma Khatun Usha & Rodolfo Calderon & Elizabeth Snella & Abigail Gorden & Yudi Zhang & Paul Gadue & Deborah L. French & Karin S. Dorman & Antonella Fid, 2023. "Nod1-dependent NF-kB activation initiates hematopoietic stem cell specification in response to small Rho GTPases," Nature Communications, Nature, vol. 14(1), pages 1-19, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:496:y:2013:i:7444:d:10.1038_nature12025. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.