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CLASP-mediated cortical microtubule organization guides PIN polarization axis

Author

Listed:
  • Klementina Kakar

    (Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands)

  • Hongtao Zhang

    (Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584CH Utrecht, The Netherlands
    Netherlands Proteomics Centre, Padualaan 8, 3584CH Utrecht, The Netherlands)

  • Ben Scheres

    (Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    Netherlands Proteomics Centre, Padualaan 8, 3584CH Utrecht, The Netherlands
    Wageningen University Research, Droevendaalsesteeg 1, 6708 PB Wageningen, The Netherlands)

  • Pankaj Dhonukshe

    (Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    VIB, Technologiepark 927, B-9052 Ghent, Belgium
    Ghent University, B-9052 Ghent, Belgium)

Abstract

The microtubule orientation regulators CLASP and MAP65 are shown to control the distribution of the polarity regulator PINOID kinase by controlling its retention at the plasma membrane, providing a mechanism for how polarity is established in plants.

Suggested Citation

  • Klementina Kakar & Hongtao Zhang & Ben Scheres & Pankaj Dhonukshe, 2013. "CLASP-mediated cortical microtubule organization guides PIN polarization axis," Nature, Nature, vol. 495(7442), pages 529-533, March.
    • Handle: RePEc:nat:nature:v:495:y:2013:i:7442:d:10.1038_nature11980
    DOI: 10.1038/nature11980
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