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Rewriting a genome

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  • Emmanuelle Charpentier

    (Emmanuelle Charpentier is at the Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany, in the Laboratory for Molecular Infection Medicine Sweden, UmeƄ University, Sweden, and at the Hanover Medical School, Hanover, Germany.)

  • Jennifer A. Doudna

    (Jennifer A. Doudna is at the Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, California 94720, USA, Lawrence Berkeley National Laboratory, Berkeley.)

Abstract

A bacterial enzyme that uses guide RNA molecules to target DNA for cleavage has been adopted as a programmable tool to site-specifically modify genomes of cells and organisms, from bacteria and human cells to whole zebrafish.

Suggested Citation

  • Emmanuelle Charpentier & Jennifer A. Doudna, 2013. "Rewriting a genome," Nature, Nature, vol. 495(7439), pages 50-51, March.
  • Handle: RePEc:nat:nature:v:495:y:2013:i:7439:d:10.1038_495050a
    DOI: 10.1038/495050a
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    Cited by:

    1. Shanmugam, Sabarathinam & Ngo, Huu-Hao & Wu, Yi-Rui, 2020. "Advanced CRISPR/Cas-based genome editing tools for microbial biofuels production: A review," Renewable Energy, Elsevier, vol. 149(C), pages 1107-1119.

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