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Fucose sensing regulates bacterial intestinal colonization

Author

Listed:
  • Alline R. Pacheco

    (University of Texas Southwestern Medical Center
    University of Texas Southwestern Medical Center)

  • Meredith M. Curtis

    (University of Texas Southwestern Medical Center
    University of Texas Southwestern Medical Center)

  • Jennifer M. Ritchie

    (Brigham and Women’s Hospital, Harvard Medical School)

  • Diana Munera

    (Brigham and Women’s Hospital, Harvard Medical School)

  • Matthew K. Waldor

    (Brigham and Women’s Hospital, Harvard Medical School)

  • Cristiano G. Moreira

    (University of Texas Southwestern Medical Center
    University of Texas Southwestern Medical Center)

  • Vanessa Sperandio

    (University of Texas Southwestern Medical Center
    University of Texas Southwestern Medical Center)

Abstract

FusKR, a fucose-sensing two-component system, has been identified in enterohaemorrhagic E. coli, linking fucose utilization and virulence factor gene expression and providing insight into how sensing of a host signal can facilitate bacterial colonization.

Suggested Citation

  • Alline R. Pacheco & Meredith M. Curtis & Jennifer M. Ritchie & Diana Munera & Matthew K. Waldor & Cristiano G. Moreira & Vanessa Sperandio, 2012. "Fucose sensing regulates bacterial intestinal colonization," Nature, Nature, vol. 492(7427), pages 113-117, December.
  • Handle: RePEc:nat:nature:v:492:y:2012:i:7427:d:10.1038_nature11623
    DOI: 10.1038/nature11623
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    Citations

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    Cited by:

    1. Abdulaziz Alqasim & Richard Emes & Gemma Clark & Jane Newcombe & Roberto La Ragione & Alan McNally, 2014. "Phenotypic Microarrays Suggest Escherichia coli ST131 Is Not a Metabolically Distinct Lineage of Extra-Intestinal Pathogenic E. coli," PLOS ONE, Public Library of Science, vol. 9(2), pages 1-8, February.
    2. Ádám Kerényi & Dóra Bihary & Vittorio Venturi & Sándor Pongor, 2013. "Stability of Multispecies Bacterial Communities: Signaling Networks May Stabilize Microbiomes," PLOS ONE, Public Library of Science, vol. 8(3), pages 1-10, March.
    3. Bin Liu & Lingyan Jiang & Yutao Liu & Hongmin Sun & Jun Yan & Chenbo Kang & Bin Yang, 2023. "Enterohaemorrhagic E. coli utilizes host- and microbiota-derived L-malate as a signaling molecule for intestinal colonization," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
    4. Lharbi Dridi & Fernando Altamura & Emmanuel Gonzalez & Olivia Lui & Ryszard Kubinski & Reilly Pidgeon & Adrian Montagut & Jasmine Chong & Jianguo Xia & Corinne F. Maurice & Bastien Castagner, 2023. "Identifying glycan consumers in human gut microbiota samples using metabolic labeling coupled with fluorescence-activated cell sorting," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
    5. Shuyu Li & Hengxi Sun & Jianghan Li & Yujiao Zhao & Ruiying Wang & Lei Xu & Chongyi Duan & Jialin Li & Zhuo Wang & Qinmeng Liu & Yao Wang & Songying Ouyang & Xihui Shen & Lei Zhang, 2022. "Autoinducer-2 and bile salts induce c-di-GMP synthesis to repress the T3SS via a T3SS chaperone," Nature Communications, Nature, vol. 13(1), pages 1-16, December.

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