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Controlling interneuron activity in Caenorhabditis elegans to evoke chemotactic behaviour

Author

Listed:
  • Askin Kocabas

    (FAS Center for Systems Biology, Harvard University
    Harvard University)

  • Ching-Han Shen

    (FAS Center for Systems Biology, Harvard University
    Harvard University)

  • Zengcai V. Guo

    (Janelia Farm Research Campus, Howard Hughes Medical Institute)

  • Sharad Ramanathan

    (FAS Center for Systems Biology, Harvard University
    Harvard University
    Allen Institute for Brain Science
    Harvard Stem Cell Institute, Harvard University)

Abstract

Optogenetic neuronal control of freely moving Caenorhabditis elegans to drive the animals up virtual ‘optical’ gradients combined with real-time tracking demonstrates that a single pair of interneurons is technically sufficient to determine such guided locomotion.

Suggested Citation

  • Askin Kocabas & Ching-Han Shen & Zengcai V. Guo & Sharad Ramanathan, 2012. "Controlling interneuron activity in Caenorhabditis elegans to evoke chemotactic behaviour," Nature, Nature, vol. 490(7419), pages 273-277, October.
    • Handle: RePEc:nat:nature:v:490:y:2012:i:7419:d:10.1038_nature11431
    DOI: 10.1038/nature11431
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