IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v488y2012i7411d10.1038_nature11272.html
   My bibliography  Save this article

The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming

Author

Listed:
  • Abed AlFatah Mansour

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Ohad Gafni

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Leehee Weinberger

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Asaf Zviran

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Muneef Ayyash

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Yoach Rais

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Vladislav Krupalnik

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Mirie Zerbib

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Daniela Amann-Zalcenstein

    (Weizmann Institute of Science, Rehovot 76100, Israel
    Weizmann Institute of Science, Rehovot 76100, Israel)

  • Itay Maza

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Shay Geula

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Sergey Viukov

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Liad Holtzman

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Ariel Pribluda

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Eli Canaani

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Shirley Horn-Saban

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Ido Amit

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Noa Novershtern

    (Weizmann Institute of Science, Rehovot 76100, Israel)

  • Jacob H. Hanna

    (Weizmann Institute of Science, Rehovot 76100, Israel)

Abstract

The H3K27 demethylase Utx is reported to be a critical regulator for the initiation of somatic and germ cell reprogramming.

Suggested Citation

  • Abed AlFatah Mansour & Ohad Gafni & Leehee Weinberger & Asaf Zviran & Muneef Ayyash & Yoach Rais & Vladislav Krupalnik & Mirie Zerbib & Daniela Amann-Zalcenstein & Itay Maza & Shay Geula & Sergey Viuk, 2012. "The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming," Nature, Nature, vol. 488(7411), pages 409-413, August.
    • Handle: RePEc:nat:nature:v:488:y:2012:i:7411:d:10.1038_nature11272
    DOI: 10.1038/nature11272
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature11272
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature11272?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Daniel F. Kaemena & Masahito Yoshihara & Meryam Beniazza & James Ashmore & Suling Zhao & Mårten Bertenstam & Victor Olariu & Shintaro Katayama & Keisuke Okita & Simon R. Tomlinson & Kosuke Yusa & Keis, 2023. "B1 SINE-binding ZFP266 impedes mouse iPSC generation through suppression of chromatin opening mediated by reprogramming factors," Nature Communications, Nature, vol. 14(1), pages 1-16, December.
    2. Jin Ming & Lihui Lin & Jiajun Li & Linlin Wu & Shicai Fang & Tao Huang & Yu Fu & Dong Liu & Wenhui Zhang & Chen Li & Yongzheng Yang & Yi Huang & Yue Qin & Junqi Kuang & Xingnan Huang & Liman Guo & Xia, 2024. "Cell fate decision by a morphogen-transcription factor-chromatin modifier axis," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
    3. Mengwen Hu & Yu-Han Yeh & Yasuhisa Munakata & Hironori Abe & Akihiko Sakashita & So Maezawa & Miguel Vidal & Haruhiko Koseki & Neil Hunter & Richard M. Schultz & Satoshi H. Namekawa, 2022. "PRC1-mediated epigenetic programming is required to generate the ovarian reserve," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
    4. Chuan Gao & Ian C McDowell & Shiwen Zhao & Christopher D Brown & Barbara E Engelhardt, 2016. "Context Specific and Differential Gene Co-expression Networks via Bayesian Biclustering," PLOS Computational Biology, Public Library of Science, vol. 12(7), pages 1-39, July.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:488:y:2012:i:7411:d:10.1038_nature11272. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.