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Site-specific DICER and DROSHA RNA products control the DNA-damage response

Author

Listed:
  • Sofia Francia

    (IFOM Foundation - FIRC Institute of Molecular Oncology Foundation, Via Adamello 16, 20139 Milan, Italy
    Center for Genomic Science of IIT@SEMM, Istituto Italiano di Tecnologia, at the IFOM-IEO Campus, Via Adamello 16, 20139 Milan, Italy)

  • Flavia Michelini

    (IFOM Foundation - FIRC Institute of Molecular Oncology Foundation, Via Adamello 16, 20139 Milan, Italy)

  • Alka Saxena

    (Omics Science Center, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan)

  • Dave Tang

    (Omics Science Center, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan)

  • Michiel de Hoon

    (Omics Science Center, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan)

  • Viviana Anelli

    (IFOM Foundation - FIRC Institute of Molecular Oncology Foundation, Via Adamello 16, 20139 Milan, Italy
    Present addresses: Departments of Surgery and Medicine, Weill Cornell Medical College and New York Presbyterian Hospital, 1300 York Avenue, New York, New York 10065, USA (V.A.); Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, 76344 Karlsruhe, Germany (M.M.).)

  • Marina Mione

    (IFOM Foundation - FIRC Institute of Molecular Oncology Foundation, Via Adamello 16, 20139 Milan, Italy
    Present addresses: Departments of Surgery and Medicine, Weill Cornell Medical College and New York Presbyterian Hospital, 1300 York Avenue, New York, New York 10065, USA (V.A.); Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, 76344 Karlsruhe, Germany (M.M.).)

  • Piero Carninci

    (Omics Science Center, RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan)

  • Fabrizio d’Adda di Fagagna

    (IFOM Foundation - FIRC Institute of Molecular Oncology Foundation, Via Adamello 16, 20139 Milan, Italy
    Istituto di Genetica Molecolare, Consiglio Nazionale delle Ricerche)

Abstract

Small non-coding RNAs have been implicated in the regulation of many processes; now a novel class of these RNAs is identified as having a role in the DNA-damage response.

Suggested Citation

  • Sofia Francia & Flavia Michelini & Alka Saxena & Dave Tang & Michiel de Hoon & Viviana Anelli & Marina Mione & Piero Carninci & Fabrizio d’Adda di Fagagna, 2012. "Site-specific DICER and DROSHA RNA products control the DNA-damage response," Nature, Nature, vol. 488(7410), pages 231-235, August.
    • Handle: RePEc:nat:nature:v:488:y:2012:i:7410:d:10.1038_nature11179
    DOI: 10.1038/nature11179
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    Cited by:

    1. Ilaria Rosso & Corey Jones-Weinert & Francesca Rossiello & Matteo Cabrini & Silvia Brambillasca & Leonel Munoz-Sagredo & Zeno Lavagnino & Emanuele Martini & Enzo Tedone & Massimiliano Garre’ & Julio A, 2023. "Alternative lengthening of telomeres (ALT) cells viability is dependent on C-rich telomeric RNAs," Nature Communications, Nature, vol. 14(1), pages 1-16, December.

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