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Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration

Author

Listed:
  • Panteleimon Rompolas

    (Yale Stem Cell Center, Yale Cancer Center, Yale School of Medicine)

  • Elizabeth R. Deschene

    (Yale Stem Cell Center, Yale Cancer Center, Yale School of Medicine)

  • Giovanni Zito

    (Yale Stem Cell Center, Yale Cancer Center, Yale School of Medicine)

  • David G. Gonzalez

    (Yale School of Medicine)

  • Ichiko Saotome

    (Yale Stem Cell Center, Yale Cancer Center, Yale School of Medicine)

  • Ann M. Haberman

    (Yale School of Medicine)

  • Valentina Greco

    (Yale Stem Cell Center, Yale Cancer Center, Yale School of Medicine)

Abstract

A non-invasive method is used to study and manipulate hair-follicle regeneration over time in live mice, and shows that hair growth involves spatially regulated cell divisions, cellular reorganization and migration of epithelial cells, and that the mesenchyme is required for hair growth.

Suggested Citation

  • Panteleimon Rompolas & Elizabeth R. Deschene & Giovanni Zito & David G. Gonzalez & Ichiko Saotome & Ann M. Haberman & Valentina Greco, 2012. "Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration," Nature, Nature, vol. 487(7408), pages 496-499, July.
    • Handle: RePEc:nat:nature:v:487:y:2012:i:7408:d:10.1038_nature11218
    DOI: 10.1038/nature11218
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    Cited by:

    1. Hadas Sibony-Benyamini & Emil Aamar & David Enshell-Seijffers, 2023. "Hdac1 and Hdac2 regulate the quiescent state and survival of hair-follicle mesenchymal niche," Nature Communications, Nature, vol. 14(1), pages 1-17, December.

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