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Structure of the δ-opioid receptor bound to naltrindole

Author

Listed:
  • Sébastien Granier

    (Stanford University School of Medicine
    CNRS UMR 5203, and INSERM U661, and Université Montpellier 1 et 2, Institut de Génomique Fonctionnelle, Montpellier 34094, France)

  • Aashish Manglik

    (Stanford University School of Medicine)

  • Andrew C. Kruse

    (Stanford University School of Medicine)

  • Tong Sun Kobilka

    (Stanford University School of Medicine)

  • Foon Sun Thian

    (Stanford University School of Medicine)

  • William I. Weis

    (Stanford University School of Medicine
    Stanford University School of Medicine)

  • Brian K. Kobilka

    (Stanford University School of Medicine)

Abstract

The X-ray crystal structure of the mouse δ-opioid receptor in complex with the subtype-selective antagonist naltrindole is reported.

Suggested Citation

  • Sébastien Granier & Aashish Manglik & Andrew C. Kruse & Tong Sun Kobilka & Foon Sun Thian & William I. Weis & Brian K. Kobilka, 2012. "Structure of the δ-opioid receptor bound to naltrindole," Nature, Nature, vol. 485(7398), pages 400-404, May.
  • Handle: RePEc:nat:nature:v:485:y:2012:i:7398:d:10.1038_nature11111
    DOI: 10.1038/nature11111
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    Cited by:

    1. Jun Yu & Amit Kumar & Xuefeng Zhang & Charlotte Martin & Kevin Van holsbeeck & Pierre Raia & Antoine Koehl & Toon Laeremans & Jan Steyaert & Aashish Manglik & Steven Ballet & Andreas Boland & Miriam S, 2024. "Structural basis of μ-opioid receptor targeting by a nanobody antagonist," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
    2. Sarah Meulebrouck & Judith Merrheim & Gurvan Queniat & Cyril Bourouh & Mehdi Derhourhi & Mathilde Boissel & Xiaoyan Yi & Alaa Badreddine & Raphaël Boutry & Audrey Leloire & Bénédicte Toussaint & Souhi, 2024. "Functional genetics reveals the contribution of delta opioid receptor to type 2 diabetes and beta-cell function," Nature Communications, Nature, vol. 15(1), pages 1-12, December.

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