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The anti-Shine–Dalgarno sequence drives translational pausing and codon choice in bacteria

Author

Listed:
  • Gene-Wei Li

    (Howard Hughes Medical Institute, University of California)

  • Eugene Oh

    (Howard Hughes Medical Institute, University of California)

  • Jonathan S. Weissman

    (Howard Hughes Medical Institute, University of California)

Abstract

Internal Shine–Dalgarno-like sequences in bacterial messenger RNA determine the elongation rate of protein synthesis and synonymous codon usage.

Suggested Citation

  • Gene-Wei Li & Eugene Oh & Jonathan S. Weissman, 2012. "The anti-Shine–Dalgarno sequence drives translational pausing and codon choice in bacteria," Nature, Nature, vol. 484(7395), pages 538-541, April.
    • Handle: RePEc:nat:nature:v:484:y:2012:i:7395:d:10.1038_nature10965
    DOI: 10.1038/nature10965
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    Cited by:

    1. Owain J. Bryant & Filip Lastovka & Jessica Powell & Betty Y. -W. Chung, 2023. "The distinct translational landscapes of gram-negative Salmonella and gram-positive Listeria," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
    2. Alexey A Gritsenko & Marc Hulsman & Marcel J T Reinders & Dick de Ridder, 2015. "Unbiased Quantitative Models of Protein Translation Derived from Ribosome Profiling Data," PLOS Computational Biology, Public Library of Science, vol. 11(8), pages 1-26, August.
    3. Bin Shao & Jiawei Yan & Jing Zhang & Lili Liu & Ye Chen & Allen R. Buskirk, 2024. "Riboformer: a deep learning framework for predicting context-dependent translation dynamics," Nature Communications, Nature, vol. 15(1), pages 1-10, December.
    4. Pietro Bongini & Niccolò Pancino & Veronica Lachi & Caterina Graziani & Giorgia Giacomini & Paolo Andreini & Monica Bianchini, 2024. "Point-Wise Ribosome Translation Speed Prediction with Recurrent Neural Networks," Mathematics, MDPI, vol. 12(3), pages 1-12, January.

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