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MAP and kinesin-dependent nuclear positioning is required for skeletal muscle function

Author

Listed:
  • Thomas Metzger

    (Program in Developmental Biology, Sloan-Kettering Institute
    Weill Graduate School of Medical Sciences of Cornell University)

  • Vincent Gache

    (UMR S 787 INSERM, Université Pierre et Marie Curie Paris 6)

  • Mu Xu

    (Program in Developmental Biology, Sloan-Kettering Institute)

  • Bruno Cadot

    (UMR S 787 INSERM, Université Pierre et Marie Curie Paris 6)

  • Eric S. Folker

    (Program in Developmental Biology, Sloan-Kettering Institute)

  • Brian E. Richardson

    (Program in Developmental Biology, Sloan-Kettering Institute)

  • Edgar R. Gomes

    (UMR S 787 INSERM, Université Pierre et Marie Curie Paris 6
    Groupe Hospitalier Pitié-Salpêtrière, Institut de Myologie)

  • Mary K. Baylies

    (Program in Developmental Biology, Sloan-Kettering Institute
    Weill Graduate School of Medical Sciences of Cornell University)

Abstract

Skeletal muscle cells are multinucleate, and improper positioning of the nuclei contributes to muscle dysfunction.

Suggested Citation

  • Thomas Metzger & Vincent Gache & Mu Xu & Bruno Cadot & Eric S. Folker & Brian E. Richardson & Edgar R. Gomes & Mary K. Baylies, 2012. "MAP and kinesin-dependent nuclear positioning is required for skeletal muscle function," Nature, Nature, vol. 484(7392), pages 120-124, April.
    • Handle: RePEc:nat:nature:v:484:y:2012:i:7392:d:10.1038_nature10914
    DOI: 10.1038/nature10914
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    Citations

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    Cited by:

    1. Agnes Adler & Mamata Bangera & J. Wouter Beugelink & Salima Bahri & Hugo Ingen & Carolyn A. Moores & Marc Baldus, 2024. "A structural and dynamic visualization of the interaction between MAP7 and microtubules," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
    2. Cátia Silva Janota & Andreia Pinto & Anna Pezzarossa & Pedro Machado & Judite Costa & Pedro Campinho & Cláudio A. Franco & Edgar R. Gomes, 2022. "Shielding of actin by the endoplasmic reticulum impacts nuclear positioning," Nature Communications, Nature, vol. 13(1), pages 1-13, December.

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