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Cysteinyl leukotriene type I receptor desensitization sustains Ca2+-dependent gene expression

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Listed:
  • Siaw-Wei Ng

    (Anatomy and Genetics, University of Oxford, Parks Road, Oxford OX1 3PT, UK)

  • Daniel Bakowski

    (Anatomy and Genetics, University of Oxford, Parks Road, Oxford OX1 3PT, UK)

  • Charmaine Nelson

    (Anatomy and Genetics, University of Oxford, Parks Road, Oxford OX1 3PT, UK)

  • Ravi Mehta

    (Anatomy and Genetics, University of Oxford, Parks Road, Oxford OX1 3PT, UK)

  • Robert Almeyda

    (John Radcliffe Hospital, Oxford OX3 9DH, UK)

  • Grant Bates

    (John Radcliffe Hospital, Oxford OX3 9DH, UK)

  • Anant B. Parekh

    (Anatomy and Genetics, University of Oxford, Parks Road, Oxford OX1 3PT, UK)

Abstract

Rather than turning off the biological response, desensitization of the cysteinyl leukotriene type I receptor sustains long-term signalling in the immune system.

Suggested Citation

  • Siaw-Wei Ng & Daniel Bakowski & Charmaine Nelson & Ravi Mehta & Robert Almeyda & Grant Bates & Anant B. Parekh, 2012. "Cysteinyl leukotriene type I receptor desensitization sustains Ca2+-dependent gene expression," Nature, Nature, vol. 482(7383), pages 111-115, February.
    • Handle: RePEc:nat:nature:v:482:y:2012:i:7383:d:10.1038_nature10731
    DOI: 10.1038/nature10731
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