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A question of library design

Author

Listed:
  • Philip J. Hajduk

    (Abbott Laboratories, Abbott Park, Illinois 60064, USA. philip.hajduk@abbott.com)

  • Warren R. J. D. Galloway

    (University of Cambridge, Cambridge CB2 1EW, UK. spring@ch.cam.ac.uk)

  • David R. Spring

    (University of Cambridge, Cambridge CB2 1EW, UK. spring@ch.cam.ac.uk)

Abstract

Two approaches have emerged for creating libraries of compounds for use in biological screening assays for drug discovery — fragment-based ligand design and diversity-oriented synthesis. Advocates of each approach discuss their favoured strategy.

Suggested Citation

  • Philip J. Hajduk & Warren R. J. D. Galloway & David R. Spring, 2011. "A question of library design," Nature, Nature, vol. 470(7332), pages 42-43, February.
    • Handle: RePEc:nat:nature:v:470:y:2011:i:7332:d:10.1038_470042a
    DOI: 10.1038/470042a
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    Cited by:

    1. Brender, Nathalie & Markov, Iliya, 2013. "Risk perception and risk management in cloud computing: Results from a case study of Swiss companies," International Journal of Information Management, Elsevier, vol. 33(5), pages 726-733.

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