IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v466y2010i7302d10.1038_nature09142.html
   My bibliography  Save this article

The male mouse pheromone ESP1 enhances female sexual receptive behaviour through a specific vomeronasal receptor

Author

Listed:
  • Sachiko Haga

    (Graduate School of Agricultural and Life Sciences, The University of Tokyo)

  • Tatsuya Hattori

    (Companion Animal Research, School of Veterinary Medicine, Azabu University)

  • Toru Sato

    (Graduate School of Agricultural and Life Sciences, The University of Tokyo)

  • Koji Sato

    (Graduate School of Agricultural and Life Sciences, The University of Tokyo)

  • Soichiro Matsuda

    (Graduate School of Agricultural and Life Sciences, The University of Tokyo)

  • Reiko Kobayakawa

    (Osaka Bioscience Institute)

  • Hitoshi Sakano

    (Graduate School of Science, The University of Tokyo)

  • Yoshihiro Yoshihara

    (Laboratory for Neurobiology of Synapse, RIKEN Brain Science Institute)

  • Takefumi Kikusui

    (Companion Animal Research, School of Veterinary Medicine, Azabu University)

  • Kazushige Touhara

    (Graduate School of Agricultural and Life Sciences, The University of Tokyo)

Abstract

Driven to tears Pheromones and their detection by the vomeronasal organ are known to govern social behaviour in mice, but few chemical signals have been linked to specific behavioural responses. Haga et al. now show that the ESP1 peptide secreted in male tears makes females sexually receptive, and have identified its specific vomeronasal receptor (V2Rp5) and the sex-specific neuronal circuits activated during the behavioural response. Whether such 'labelled line' logic extends to the regulation of reproductive behaviour in other mammals remains unclear.

Suggested Citation

  • Sachiko Haga & Tatsuya Hattori & Toru Sato & Koji Sato & Soichiro Matsuda & Reiko Kobayakawa & Hitoshi Sakano & Yoshihiro Yoshihara & Takefumi Kikusui & Kazushige Touhara, 2010. "The male mouse pheromone ESP1 enhances female sexual receptive behaviour through a specific vomeronasal receptor," Nature, Nature, vol. 466(7302), pages 118-122, July.
    • Handle: RePEc:nat:nature:v:466:y:2010:i:7302:d:10.1038_nature09142
    DOI: 10.1038/nature09142
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature09142
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature09142?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Anat Kahan & Yoram Ben-Shaul, 2016. "Extracting Behaviorally Relevant Traits from Natural Stimuli: Benefits of Combinatorial Representations at the Accessory Olfactory Bulb," PLOS Computational Biology, Public Library of Science, vol. 12(3), pages 1-25, March.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:466:y:2010:i:7302:d:10.1038_nature09142. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.