IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v459y2009i7248d10.1038_nature08074.html
   My bibliography  Save this article

A spatial gradient coordinates cell size and mitotic entry in fission yeast

Author

Listed:
  • James B. Moseley

    (The Rockefeller University, New York, New York 10065, USA)

  • Adeline Mayeux

    (Institut Curie, Centre de Recherche and CNRS UMR144)

  • Anne Paoletti

    (Institut Curie, Centre de Recherche and CNRS UMR144)

  • Paul Nurse

    (The Rockefeller University, New York, New York 10065, USA)

Abstract

A time to divide Proliferating cells divide when they reach a certain size owing to regulated activity of cyclin-dependent kinase (Cdk1), but the links between Cdk1 regulators and mechanisms monitoring cell size have been elusive. Two papers in this issue describe how a fission yeast kinase Pom1, known to be a determinant of cell polarity, forms a polar gradient within the cell, which measures the length of the rod-shaped cells and induces cell division via negative regulation of the Cdk1 inhibitor Wee1.

Suggested Citation

  • James B. Moseley & Adeline Mayeux & Anne Paoletti & Paul Nurse, 2009. "A spatial gradient coordinates cell size and mitotic entry in fission yeast," Nature, Nature, vol. 459(7248), pages 857-860, June.
    • Handle: RePEc:nat:nature:v:459:y:2009:i:7248:d:10.1038_nature08074
    DOI: 10.1038/nature08074
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature08074
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature08074?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Rashidi, Armin & Shelton, Deborah E. & Michod, Richard E., 2015. "A Darwinian approach to the origin of life cycles with group properties," Theoretical Population Biology, Elsevier, vol. 102(C), pages 76-84.
    2. Gu, Xinyue & Chen, Pengyu & Fan, Chao, 2024. "Socio-demographic inequalities in the impacts of extreme temperatures on population mobility11This research received no specific grant from any funding agency, commercial or not-for-profit sectors," Journal of Transport Geography, Elsevier, vol. 114(C).

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:459:y:2009:i:7248:d:10.1038_nature08074. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.