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Imaging stem-cell-driven regeneration in mammals

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  • Timm Schroeder

    (Institute of Stem Cell Research, Helmholtz Zentrum München – German Research Center for Environmental Health, Ingolstädter Landstrasse 1)

Abstract

The ability to observe biological processes continuously, instead of at discrete time points, holds great promise for the study of tissue regeneration. Ideally, single cells would be followed continuously within large tissue volumes (such as organs) over long periods of time. Technical limitations, however, preclude such studies. But, recently, there have been improvements in imaging technologies and biologically compatible labelling agents. Together with new insights into the molecular characteristics of stem cells, which are ultimately responsible for the regenerative potential of all tissues, researchers are now much closer to applying single-cell imaging approaches to research into regeneration and its clinical applications.

Suggested Citation

  • Timm Schroeder, 2008. "Imaging stem-cell-driven regeneration in mammals," Nature, Nature, vol. 453(7193), pages 345-351, May.
  • Handle: RePEc:nat:nature:v:453:y:2008:i:7193:d:10.1038_nature07043
    DOI: 10.1038/nature07043
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    Cited by:

    1. Geethika Arekatla & Stavroula Skylaki & David Corredor Suarez & Hartland Jackson & Denis Schapiro & Stefanie Engler & Markus Auler & German Camargo Ortega & Simon Hastreiter & Andreas Reimann & Dirk L, 2024. "Identification of an embryonic differentiation stage marked by Sox1 and FoxA2 co-expression using combined cell tracking and high dimensional protein imaging," Nature Communications, Nature, vol. 15(1), pages 1-16, December.

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