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The search for new cardiovascular biomarkers

Author

Listed:
  • Robert E. Gerszten

    (Massachusetts General Hospital
    Massachusetts General Hospital, Center for Immunology and Inflammatory Diseases)

  • Thomas J. Wang

    (Massachusetts General Hospital, Center for Immunology and Inflammatory Diseases)

Abstract

Despite considerable advances in the treatment of cardiovascular disease, it remains the leading cause of death in developed countries. Assessment of classic cardiovascular risk factors — including high blood pressure, diabetes and smoking — has a central role in disease prevention. However, many individuals with coronary heart disease (a narrowing of the blood vessels that supply the heart) have only one, or none, of the classic risk factors. Thus, new biomarkers are needed to augment the information obtained from traditional indicators and to illuminate disease mechanisms.

Suggested Citation

  • Robert E. Gerszten & Thomas J. Wang, 2008. "The search for new cardiovascular biomarkers," Nature, Nature, vol. 451(7181), pages 949-952, February.
  • Handle: RePEc:nat:nature:v:451:y:2008:i:7181:d:10.1038_nature06802
    DOI: 10.1038/nature06802
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    Cited by:

    1. Usman A. Tahir & Daniel H. Katz & Julian Avila-Pachecho & Alexander G. Bick & Akhil Pampana & Jeremy M. Robbins & Zhi Yu & Zsu-Zsu Chen & Mark D. Benson & Daniel E. Cruz & Debby Ngo & Shuliang Deng & , 2022. "Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals," Nature Communications, Nature, vol. 13(1), pages 1-16, December.

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