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Reducing the global burden of tuberculosis: the contribution of improved diagnostics

Author

Listed:
  • Emmett Keeler

    (RAND Corporation)

  • Mark D. Perkins

    (Foundation for Innovative New Diagnostics)

  • Peter Small

    (Bill & Melinda Gates Foundation)

  • Christy Hanson

    (United States Agency for International Development)

  • Steven Reed

    (Infectious Disease Research Institute)

  • Jane Cunningham

    (World Health Organization, Avenue Appia)

  • Julia E. Aledort

    (RAND Corporation)

  • Lee Hillborne

    (RAND Corporation)

  • Maria E. Rafael

    (RAND Corporation)

  • Federico Girosi

    (RAND Corporation)

  • Christopher Dye

    (World Health Organization, Avenue Appia)

Abstract

We estimated the impact of hypothetical new diagnostic tests for tuberculosis (TB) in patients with persistent cough in developing countries. We found that a variety of new tests could help better identify TB cases and target treatment, thereby reducing the burden of disease.

Suggested Citation

  • Emmett Keeler & Mark D. Perkins & Peter Small & Christy Hanson & Steven Reed & Jane Cunningham & Julia E. Aledort & Lee Hillborne & Maria E. Rafael & Federico Girosi & Christopher Dye, 2006. "Reducing the global burden of tuberculosis: the contribution of improved diagnostics," Nature, Nature, vol. 444(1), pages 49-57, November.
    • Handle: RePEc:nat:nature:v:444:y:2006:i:1:d:10.1038_nature05446
    DOI: 10.1038/nature05446
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    Cited by:

    1. David W Dowdy & Maria C Lourenço & Solange C Cavalcante & Valeria Saraceni & Bonnie King & Jonathan E Golub & David Bishai & Betina Durovni & Richard E Chaisson & Susan E Dorman, 2008. "Impact and Cost-Effectiveness of Culture for Diagnosis of Tuberculosis in HIV-Infected Brazilian Adults," PLOS ONE, Public Library of Science, vol. 3(12), pages 1-8, December.
    2. Simone Peart Boyce & Andrés A. Berruti & Helen Connolly & Miriam Schneidman, 2015. "Evaluating the Economic and Health Impacts of Investing in Laboratories in East Africa: Development and Application of a Conceptual Framework," Health, Nutrition and Population (HNP) Discussion Paper Series 97386, The World Bank.
    3. Miraj ud-din & Aqel Albutti & Asad Ullah & Saba Ismail & Sajjad Ahmad & Anam Naz & Muhammad Khurram & Mahboob ul Haq & Zobia Afsheen & Youness El Bakri & Muhammad Salman & Bilal Shaker & Muhammad Tahi, 2022. "Vaccinomics to Design a Multi-Epitopes Vaccine for Acinetobacter baumannii," IJERPH, MDPI, vol. 19(9), pages 1-26, May.
    4. Swati Jha & Nazir Ismail & David Clark & James J Lewis & Shaheed Omar & Andries Dreyer & Violet Chihota & Gavin Churchyard & David W Dowdy, 2016. "Cost-Effectiveness of Automated Digital Microscopy for Diagnosis of Active Tuberculosis," PLOS ONE, Public Library of Science, vol. 11(6), pages 1-11, June.

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