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Identification of a mammalian mitochondrial porphyrin transporter

Author

Listed:
  • Partha C. Krishnamurthy

    (Department of Pharmaceutical Sciences)

  • Guoqing Du

    (Department of Pharmaceutical Sciences)

  • Yu Fukuda

    (Department of Pharmaceutical Sciences
    University of Tennessee Health Sciences Center)

  • Daxi Sun

    (Department of Pharmaceutical Sciences)

  • Janardhan Sampath

    (Department of Pharmaceutical Sciences)

  • Kelly E. Mercer

    (Department of Pharmaceutical Sciences)

  • Junfeng Wang

    (Department of Genetics and Tumor Cell Biology)

  • Beatriz Sosa-Pineda

    (Department of Genetics and Tumor Cell Biology)

  • K. Gopal Murti

    (the Scientific Imaging Resource Center, St. Jude Children's Research Hospital)

  • John D. Schuetz

    (Department of Pharmaceutical Sciences)

Abstract

The transport of porphyrins across the mitochondrial membrane is important for cellular processes. The ABC transporter Abcb6 (an energy-requiring transporter) plays a key role not only in mitochondrial porphyrin transport but also in the upregulation of haeme biosynthesis.

Suggested Citation

  • Partha C. Krishnamurthy & Guoqing Du & Yu Fukuda & Daxi Sun & Janardhan Sampath & Kelly E. Mercer & Junfeng Wang & Beatriz Sosa-Pineda & K. Gopal Murti & John D. Schuetz, 2006. "Identification of a mammalian mitochondrial porphyrin transporter," Nature, Nature, vol. 443(7111), pages 586-589, October.
    • Handle: RePEc:nat:nature:v:443:y:2006:i:7111:d:10.1038_nature05125
    DOI: 10.1038/nature05125
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    Cited by:

    1. Stefanie A. Baril & Katie A. Wilson & Md Munan Shaik & Yu Fukuda & Robyn A. Umans & Alessandro Barbieri & John Lynch & Tomoka Gose & Alexander Myasnikov & Michael L. Oldham & Yao Wang & Jingwen Zhu & , 2024. "The role of ATP-binding Cassette subfamily B member 6 in the inner ear," Nature Communications, Nature, vol. 15(1), pages 1-17, December.

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