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A common progenitor for haematopoietic and endothelial lineages in the zebrafish gastrula

Author

Listed:
  • Kevin M. Vogeli

    (Department of Biochemistry and Biophysics
    Department of Anatomy
    University of California, San Francisco)

  • Suk-Won Jin

    (Department of Biochemistry and Biophysics
    University of California, San Francisco
    University of North Carolina at Chapel Hill)

  • Gail R. Martin

    (Department of Anatomy
    University of California, San Francisco)

  • Didier Y. R. Stainier

    (Department of Biochemistry and Biophysics
    University of California, San Francisco)

Abstract

Haemangioblast at last The haemangioblast is a biopotential precursor of both blood and endothelial cells that has been hypothesized to exist for almost 100 years, but for which formal proof has been lacking. Vogeli et al. now provide in vivo evidence for its existence. High-resolution, single cell lineage studies of zebrafish embryos show that the haemangioblast is present in the early fish embryo, and also reveal new information about its structure and function.

Suggested Citation

  • Kevin M. Vogeli & Suk-Won Jin & Gail R. Martin & Didier Y. R. Stainier, 2006. "A common progenitor for haematopoietic and endothelial lineages in the zebrafish gastrula," Nature, Nature, vol. 443(7109), pages 337-339, September.
    • Handle: RePEc:nat:nature:v:443:y:2006:i:7109:d:10.1038_nature05045
    DOI: 10.1038/nature05045
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    Cited by:

    1. Karin D. Prummel & Helena L. Crowell & Susan Nieuwenhuize & Eline C. Brombacher & Stephan Daetwyler & Charlotte Soneson & Jelena Kresoja-Rakic & Agnese Kocere & Manuel Ronner & Alexander Ernst & Zahra, 2022. "Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma," Nature Communications, Nature, vol. 13(1), pages 1-21, December.

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