IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v438y2005i7070d10.1038_nature04198.html
   My bibliography  Save this article

A RhoGDP dissociation inhibitor spatially regulates growth in root hair cells

Author

Listed:
  • Rachel J. Carol

    (Department of Cell and Developmental Biology
    University of Northumbria)

  • Seiji Takeda

    (Department of Cell and Developmental Biology)

  • Paul Linstead

    (Department of Cell and Developmental Biology)

  • Marcus C. Durrant

    (John Innes Centre
    École Pratique des Hautes Études)

  • Hana Kakesova

    (Charles University
    Academy of Sciences of the Czech Republic)

  • Paul Derbyshire

    (Department of Cell and Developmental Biology)

  • Sinéad Drea

    (Department of Cell and Developmental Biology
    Yale University)

  • Viktor Zarsky

    (Charles University
    Academy of Sciences of the Czech Republic)

  • Liam Dolan

    (Department of Cell and Developmental Biology)

Abstract

Root hairs are cellular protuberances extending from the root surface into the soil; there they provide access to immobile inorganic ions such as phosphate, which are essential for growth1. Their cylindrical shape results from a polarized mechanism of cell expansion called tip growth in which elongation is restricted to a small area at the surface of the hair-forming cell (trichoblast) tip2,3,4. Here we identify proteins that spatially control the sites at which cell growth occurs by isolating Arabidopsis mutants (scn1) that develop ectopic sites of growth on trichoblasts. We cloned SCN1 and showed that SCN1 is a RhoGTPase GDP dissociation inhibitor (RhoGDI) that spatially restricts the sites of growth to a single point on the trichoblast. We showed previously that localized production of reactive oxygen species by RHD2/AtrbohC NADPH oxidase is required for hair growth5; here we show that SCN1/AtrhoGDI1 is a component of the mechanism that focuses RHD2/AtrbohC-catalysed production of reactive oxygen species to hair tips during wild-type development. We propose that the spatial organization of growth in plant cells requires the local RhoGDI-regulated activation of the RHD2/AtrbohC NADPH oxidase.

Suggested Citation

  • Rachel J. Carol & Seiji Takeda & Paul Linstead & Marcus C. Durrant & Hana Kakesova & Paul Derbyshire & Sinéad Drea & Viktor Zarsky & Liam Dolan, 2005. "A RhoGDP dissociation inhibitor spatially regulates growth in root hair cells," Nature, Nature, vol. 438(7070), pages 1013-1016, December.
    • Handle: RePEc:nat:nature:v:438:y:2005:i:7070:d:10.1038_nature04198
    DOI: 10.1038/nature04198
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature04198
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature04198?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Jingtong Ruan & Linyu Lai & Hongxin Ou & Peishan Yi, 2023. "Two subtypes of GTPase-activating proteins coordinate tip growth and cell size regulation in Physcomitrium patens," Nature Communications, Nature, vol. 14(1), pages 1-16, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:438:y:2005:i:7070:d:10.1038_nature04198. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.