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R gene expression induced by a type-III effector triggers disease resistance in rice

Author

Listed:
  • Keyu Gu

    (National University of Singapore)

  • Bing Yang

    (Kansas State University)

  • Dongsheng Tian

    (National University of Singapore)

  • Lifang Wu

    (National University of Singapore)

  • Dongjiang Wang

    (National University of Singapore
    Chinese Academy of Sciences)

  • Chellamma Sreekala

    (National University of Singapore
    National Institute of Agrobiological Sciences)

  • Fan Yang

    (National University of Singapore
    Institute of Molecular and Cell Biology)

  • Zhaoqing Chu

    (National University of Singapore
    Genome Institute of Singapore)

  • Guo-Liang Wang

    (National University of Singapore
    Ohio State University)

  • Frank F. White

    (Kansas State University)

  • Zhongchao Yin

    (National University of Singapore)

Abstract

Disease resistance (R) genes in plants encode products that specifically recognise incompatible pathogens and trigger a cascade of events leading to disease resistance in the host plant1. R-gene specificity is dictated by both host R genes and cognate avirulence (avr) genes in pathogens2,3. However, the basis of gene-for-gene specificity is not well understood. Here, we report the cloning of the R gene Xa27 from rice and the cognate avr gene avrXa27 from Xanthomonas oryzae pv. oryzae. Resistant and susceptible alleles of Xa27 encode identical proteins. However, expression of only the resistant allele occurs when a rice plant is challenged by bacteria harbouring avrXa27, whose product is a nuclear localized type-III effector. Induction of Xa27 occurs only in the immediate vicinity of infected tissue, whereas ectopic expression of Xa27 resulted in resistance to otherwise compatible strains of the pathogen. Thus Xa27 specificity towards incompatible pathogens involves the differential expression of the R gene in the presence of the AvrXa27 effector.

Suggested Citation

  • Keyu Gu & Bing Yang & Dongsheng Tian & Lifang Wu & Dongjiang Wang & Chellamma Sreekala & Fan Yang & Zhaoqing Chu & Guo-Liang Wang & Frank F. White & Zhongchao Yin, 2005. "R gene expression induced by a type-III effector triggers disease resistance in rice," Nature, Nature, vol. 435(7045), pages 1122-1125, June.
    • Handle: RePEc:nat:nature:v:435:y:2005:i:7045:d:10.1038_nature03630
    DOI: 10.1038/nature03630
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    Cited by:

    1. Hua Wan & Jian-ping Hu & Kang-shun Li & Xu-hong Tian & Shan Chang, 2013. "Molecular Dynamics Simulations of DNA-Free and DNA-Bound TAL Effectors," PLOS ONE, Public Library of Science, vol. 8(10), pages 1-12, October.
    2. Nkulu Kabange Rolly & Qari Muhammad Imran & Hyun-Ho Kim & Nay Chi Aye & Adil Hussain & Kyung-Min Kim & Byung-Wook Yun, 2020. "Pathogen-Induced Expression of OsDHODH1 Suggests Positive Regulation of Basal Defense Against Xanthomonas oryzae pv. oryzae in Rice," Agriculture, MDPI, vol. 10(11), pages 1-19, November.

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