IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v427y2004i6973d10.1038_427411b.html
   My bibliography  Save this article

Catch-up growth and obesity in male mice

Author

Listed:
  • Susan E. Ozanne

    (University of Cambridge)

  • C. Nicholas Hales

    (University of Cambridge)

Abstract

Poor fetal growth is linked with long-term detrimental effects on health in adulthood1. Here we investigate whether the lifespan of male mice is affected by their growth rate when they were suckling and find that limiting growth during that period not only increases longevity but also protects against the life-shortening effect of an obesity-inducing diet later on. By contrast, we find that lifespan is considerably shortened if the postnatal period of growth is accelerated to make up for reduced growth in utero, and that, in addition, these mice are susceptible to the adverse effects on longevity of an obesity-inducing diet after weaning.

Suggested Citation

  • Susan E. Ozanne & C. Nicholas Hales, 2004. "Catch-up growth and obesity in male mice," Nature, Nature, vol. 427(6973), pages 411-412, January.
    • Handle: RePEc:nat:nature:v:427:y:2004:i:6973:d:10.1038_427411b
    DOI: 10.1038/427411b
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/427411b
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/427411b?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Shen, Ke & Zeng, Yi, 2014. "Direct and indirect effects of childhood conditions on survival and health among male and female elderly in China," Social Science & Medicine, Elsevier, vol. 119(C), pages 207-214.
    2. Qing Wang & Jay J. Shen, 2016. "Childhood Health Status and Adulthood Cardiovascular Disease Morbidity in Rural China: Are They Related?," IJERPH, MDPI, vol. 13(6), pages 1-10, June.
    3. Case, Anne & Fertig, Angela & Paxson, Christina, 2005. "The lasting impact of childhood health and circumstance," Journal of Health Economics, Elsevier, vol. 24(2), pages 365-389, March.
    4. Lin, Ming-Jen & Liu, Elaine M., 2014. "Does in utero exposure to Illness matter? The 1918 influenza epidemic in Taiwan as a natural experiment," Journal of Health Economics, Elsevier, vol. 37(C), pages 152-163.
    5. Lin, Ming-Jen & Liu, Elaine M., 2014. "Does in utero exposure to Illness matter? The 1918 influenza epidemic in Taiwan as a natural experiment," Journal of Health Economics, Elsevier, vol. 37(C), pages 152-163.
    6. Meng, Xin & Qian, Nancy, 2006. "The Long Run Health and Economic Consequences of Famine on Survivors: Evidence from China’s Great Famine," IZA Discussion Papers 2471, Institute of Labor Economics (IZA).
    7. Pascale Chavatte-Palmer & Anne Tarrade & Delphine Rousseau-Ralliard, 2016. "Diet before and during Pregnancy and Offspring Health: The Importance of Animal Models and What Can Be Learned from Them," IJERPH, MDPI, vol. 13(6), pages 1-14, June.
    8. Xin Meng & Nancy Qian, 2009. "The Long Term Consequences of Famine on Survivors: Evidence from a Unique Natural Experiment using China's Great Famine," NBER Working Papers 14917, National Bureau of Economic Research, Inc.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:427:y:2004:i:6973:d:10.1038_427411b. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.