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Koch's postulates fulfilled for SARS virus

Author

Listed:
  • Ron A. M. Fouchier

    (Erasmus Medical Centre)

  • Thijs Kuiken

    (Erasmus Medical Centre)

  • Martin Schutten

    (Erasmus Medical Centre)

  • Geert van Amerongen

    (Erasmus Medical Centre)

  • Gerard J. J. van Doornum

    (Erasmus Medical Centre)

  • Bernadette G. van den Hoogen

    (Erasmus Medical Centre)

  • Malik Peiris

    (University of Hong Kong, University Pathology Building, Queen Mary Hospital)

  • Wilina Lim

    (Government Virus Unit, 9/F Public Health Laboratory Centre)

  • Klaus Stöhr
  • Albert D. M. E. Osterhaus

    (Erasmus Medical Centre)

Abstract

Severe acute respiratory syndrome (SARS) has recently emerged as a new human disease, resulting globally in 435 deaths from 6,234 probable cases (as of 3 May 2003). Here we provide proof from experimental infection of cynomolgus macaques (Macaca fascicularis) that the newly discovered SARS-associated coronavirus (SCV) is the aetiological agent of this disease. Our understanding of the aetiology of SARS will expedite the development of diagnostic tests, antiviral therapies and vaccines, and may allow a more concise case definition for this emerging disease.

Suggested Citation

  • Ron A. M. Fouchier & Thijs Kuiken & Martin Schutten & Geert van Amerongen & Gerard J. J. van Doornum & Bernadette G. van den Hoogen & Malik Peiris & Wilina Lim & Klaus Stöhr & Albert D. M. E. Osterhau, 2003. "Koch's postulates fulfilled for SARS virus," Nature, Nature, vol. 423(6937), pages 240-240, May.
    • Handle: RePEc:nat:nature:v:423:y:2003:i:6937:d:10.1038_423240a
    DOI: 10.1038/423240a
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