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Early origin of canonical introns

Author

Listed:
  • Alastair G. B. Simpson

    (Canadian Institute for Advanced Research, Program in Evolutionary Biology, Dalhousie University)

  • Erin K. MacQuarrie

    (Canadian Institute for Advanced Research, Program in Evolutionary Biology, Dalhousie University)

  • Andrew J. Roger

    (Canadian Institute for Advanced Research, Program in Evolutionary Biology, Dalhousie University)

Abstract

Spliceosomal introns, one of the hallmarks of eukaryotic genomes, were thought to have originated late in evolution1,2 and were assumed not to exist in eukaryotes that diverged early — until the discovery of a single intron with an aberrant splice boundary in the primitive 'protozoan' Giardia3. Here we describe introns from a close relative of Giardia, Carpediemonas membranifera, that have boundary sequences of the normal eukaryotic type, indicating that canonical introns are likely to have arisen very early in eukaryotic evolution.

Suggested Citation

  • Alastair G. B. Simpson & Erin K. MacQuarrie & Andrew J. Roger, 2002. "Early origin of canonical introns," Nature, Nature, vol. 419(6904), pages 270-270, September.
    • Handle: RePEc:nat:nature:v:419:y:2002:i:6904:d:10.1038_419270a
    DOI: 10.1038/419270a
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    Cited by:

    1. Miklos Csuros & Igor B Rogozin & Eugene V Koonin, 2011. "A Detailed History of Intron-rich Eukaryotic Ancestors Inferred from a Global Survey of 100 Complete Genomes," PLOS Computational Biology, Public Library of Science, vol. 7(9), pages 1-9, September.

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