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Phylogeny and the origin of HIV-1

Author

Listed:
  • Andrew Rambaut

    (University of Oxford)

  • David L. Robertson

    (University of Oxford)

  • Oliver G. Pybus

    (University of Oxford)

  • Martine Peeters

    (Laboratoire Retrovirus, IRD)

  • Edward C. Holmes

    (University of Oxford)

Abstract

The origin of human immunodeficiency virus type 1 (HIV-1) is controversial. We show here that viruses obtained from the Democratic Republic of Congo in Africa have a quantitatively different phylogenetic tree structure from those sampled in other parts of the world. This indicates that the structure of HIV-1 phylogenies is the result of epidemiological processes acting within human populations alone, and is not due to multiple cross-species transmission initiated by oral polio vaccination.

Suggested Citation

  • Andrew Rambaut & David L. Robertson & Oliver G. Pybus & Martine Peeters & Edward C. Holmes, 2001. "Phylogeny and the origin of HIV-1," Nature, Nature, vol. 410(6832), pages 1047-1048, April.
    • Handle: RePEc:nat:nature:v:410:y:2001:i:6832:d:10.1038_35074179
    DOI: 10.1038/35074179
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