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Challenges and opportunities for development of an AIDS vaccine

Author

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  • Gary J. Nabel

    (Vaccine Research Center, National Institutes of Allergy and Infectious Diseases, National Institutes of Health)

Abstract

Among the devastating consequences of AIDS has been its epidemic spread in the developing world. The disease has caused unprecedented suffering, debilitation, loss of life and disruption of family, social and economic stability. Because of the considerable expense and logistical difficulty in providing antiviral drugs to populations infected with the human immunodeficiency virus throughout the world, the biomedical community is looking towards vaccines to help solve this compelling problem.

Suggested Citation

  • Gary J. Nabel, 2001. "Challenges and opportunities for development of an AIDS vaccine," Nature, Nature, vol. 410(6831), pages 1002-1007, April.
    • Handle: RePEc:nat:nature:v:410:y:2001:i:6831:d:10.1038_35073500
    DOI: 10.1038/35073500
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    Cited by:

    1. Peter Gilbert & Ronald Bosch & Michael Hudgens, 2004. "Sensitivity Analysis for the Assessment of Causal Vaccine Effects on Viral Load in HIV Vaccine Trials," UW Biostatistics Working Paper Series 1031, Berkeley Electronic Press.
    2. Peter B. Gilbert & Ronald J. Bosch & Michael G. Hudgens, 2003. "Sensitivity Analysis for the Assessment of Causal Vaccine Effects on Viral Load in HIV Vaccine Trials," Biometrics, The International Biometric Society, vol. 59(3), pages 531-541, September.
    3. Ohid Yaqub, 2018. "Variation in the dynamics and performance of industrial innovation: what can we learn from vaccines and HIV vaccines?," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 27(1), pages 173-187.
    4. Bryan E. Shepherd & Peter B. Gilbert & Yannis Jemiai & Andrea Rotnitzky, 2006. "Sensitivity Analyses Comparing Outcomes Only Existing in a Subset Selected Post-Randomization, Conditional on Covariates, with Application to HIV Vaccine Trials," Biometrics, The International Biometric Society, vol. 62(2), pages 332-342, June.
    5. Peter B. Gilbert & A. J. Rossini & Raj Shankarappa, 2005. "Two-Sample Tests for Comparing Intra-Individual Genetic Sequence Diversity between Populations," Biometrics, The International Biometric Society, vol. 61(1), pages 106-117, March.

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