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Hepatocytes from non-hepatic adult stem cells

Author

Listed:
  • Malcolm R. Alison

    (Imperial College School of Medicine, Hammersmith Campus)

  • Richard Poulsom

    (Histopathology Unit, Imperial Cancer Research Fund)

  • Rosemary Jeffery

    (Histopathology Unit, Imperial Cancer Research Fund)

  • Amar P. Dhillon

    (Royal Free Campus, Royal Free and University College School of Medicine)

  • Alberto Quaglia

    (Royal Free Campus, Royal Free and University College School of Medicine)

  • Joe Jacob

    (Imperial College School of Medicine, Hammersmith Campus)

  • Marco Novelli

    (University College London)

  • Grant Prentice

    (Royal Free Campus, Royal Free and University College School of Medicine)

  • Jill Williamson

    (Human Cytogenetics Laboratory, Imperial Cancer Research Fund)

  • Nicholas A. Wright

    (Imperial College School of Medicine, Hammersmith Campus
    Histopathology Unit, Imperial Cancer Research Fund)

Abstract

Stem cells are undifferentiated long-lived cells that are capable of many rounds of division. Here we show that adult human liver cells can be derived from stem cells originating in the bone marrow or circulating outside the liver, raising the possibility that blood-system stem cells could be used clinically to generate hepatocytes for replacing damaged tissue.

Suggested Citation

  • Malcolm R. Alison & Richard Poulsom & Rosemary Jeffery & Amar P. Dhillon & Alberto Quaglia & Joe Jacob & Marco Novelli & Grant Prentice & Jill Williamson & Nicholas A. Wright, 2000. "Hepatocytes from non-hepatic adult stem cells," Nature, Nature, vol. 406(6793), pages 257-257, July.
    • Handle: RePEc:nat:nature:v:406:y:2000:i:6793:d:10.1038_35018642
    DOI: 10.1038/35018642
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