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Neutralizing noise in gene networks

Author

Listed:
  • Timothy S. Gardner

    (Cellicon Biotechnologies)

  • James J. Collins

    (Boston University)

Abstract

Noise is inherent in gene expression, and can lead to sizeable fluctuations in the concentrations of expressed RNA and proteins. But many biological processes, such as circadian rhythms, are predictable and must be robust to internal noise. New simulations and studies of synthetic gene networks indicate that negative feedback may counteract noise.

Suggested Citation

  • Timothy S. Gardner & James J. Collins, 2000. "Neutralizing noise in gene networks," Nature, Nature, vol. 405(6786), pages 520-521, June.
    • Handle: RePEc:nat:nature:v:405:y:2000:i:6786:d:10.1038_35014708
    DOI: 10.1038/35014708
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    Cited by:

    1. Liu, Pei & Ning, Li Juan, 2016. "Transitions induced by cross-correlated bounded noises and time delay in a genotype selection model," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 441(C), pages 32-39.

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