IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v404y2000i6778d10.1038_35007519.html
   My bibliography  Save this article

Genetics of body-weight regulation

Author

Listed:
  • Gregory S. Barsh

    (Beckman Center)

  • I. Sadaf Farooqi

    (University of Cambridge, Addenbrooke's Hospital)

  • Stephen O'Rahilly

    (University of Cambridge, Addenbrooke's Hospital)

Abstract

The role of genetics in obesity is twofold. Studying rare mutations in humans and model organisms provides fundamental insight into a complex physiological process, and complements population-based studies that seek to reveal primary causes. Remarkable progress has been made on both fronts, and the pace of advance is likely to accelerate as functional genomics and the human genome project expand and mature. Approaches based on mendelian and quantitative genetics may well converge, and lead ultimately to more rational and selective therapies.

Suggested Citation

  • Gregory S. Barsh & I. Sadaf Farooqi & Stephen O'Rahilly, 2000. "Genetics of body-weight regulation," Nature, Nature, vol. 404(6778), pages 644-651, April.
    • Handle: RePEc:nat:nature:v:404:y:2000:i:6778:d:10.1038_35007519
    DOI: 10.1038/35007519
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/35007519
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/35007519?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Jennifer MacKellar & Samuel W Cushman & Vipul Periwal, 2010. "Waves of Adipose Tissue Growth in the Genetically Obese Zucker Fatty Rat," PLOS ONE, Public Library of Science, vol. 5(1), pages 1-9, January.
    2. Smith, Trenton G, 2002. "Obesity and Nature's Thumbprint: How Modern Waistlines Can Inform Economic Theory," University of California at Santa Barbara, Economics Working Paper Series qt31g1m028, Department of Economics, UC Santa Barbara.
    3. Smith Trenton G. & Stoddard Christiana & Barnes Michael G, 2009. "Why the Poor Get Fat: Weight Gain and Economic Insecurity," Forum for Health Economics & Policy, De Gruyter, vol. 12(2), pages 1-31, June.
    4. Trenton Smith, 2009. "Reconciling psychology with economics: Obesity, behavioral biology, and rational overeating," Journal of Bioeconomics, Springer, vol. 11(3), pages 249-282, December.
    5. Brown, Judith E. & Broom, Dorothy H. & Nicholson, Jan M. & Bittman, Michael, 2010. "Do working mothers raise couch potato kids? Maternal employment and children's lifestyle behaviours and weight in early childhood," Social Science & Medicine, Elsevier, vol. 70(11), pages 1816-1824, June.
    6. Dang, Thang, 2017. "Body Weight and Hypertension Risk in a Developing Country," MPRA Paper 83182, University Library of Munich, Germany.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:404:y:2000:i:6778:d:10.1038_35007519. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.