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A unique circadian-rhythm photoreceptor

Author

Listed:
  • Patrick Emery

    (NSF Center for Biological Timing, Brandeis University)

  • Ralf Stanewsky

    (Zoologisches Institut, Universität Regensburg)

  • Jeffrey C. Hall

    (NSF Center for Biological Timing, Brandeis University)

  • Michael Rosbash

    (NSF Center for Biological Timing, Brandeis University
    Howard Hughes Medical Institute, Brandeis University)

Abstract

Cryptochrome proteins are critical for circadian rhythms, but their function(s) is uncertain. Here we show that a mutation in a cryptochrome (dCRY) from the fruitfly Drosophila blocks an essential photoresponse of circadian rhythms, namely arrhythmicity under constant light conditions. We conclude that dCRY acts as a key photoreceptor for circadian rhythms and that there is probably no other comparable photoreceptor in this species.

Suggested Citation

  • Patrick Emery & Ralf Stanewsky & Jeffrey C. Hall & Michael Rosbash, 2000. "A unique circadian-rhythm photoreceptor," Nature, Nature, vol. 404(6777), pages 456-457, March.
    • Handle: RePEc:nat:nature:v:404:y:2000:i:6777:d:10.1038_35006558
    DOI: 10.1038/35006558
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    Cited by:

    1. Angelique Lamaze & Chenghao Chen & Solene Leleux & Min Xu & Rebekah George & Ralf Stanewsky, 2022. "A natural timeless polymorphism allowing circadian clock synchronization in “white nights”," Nature Communications, Nature, vol. 13(1), pages 1-12, December.

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