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Induction and regulation of the IgE response

Author

Listed:
  • David B. Corry

    (Department of Medicine Baylor College of Medicine)

  • Farrah Kheradmand

    (Department of Medicine Baylor College of Medicine)

Abstract

Immunoglobulin E (IgE) is believed to be one of the major mediators of immediate hypersensitivity reactions that underlie atopic conditions such as urticaria, seasonal allergy, asthma and anaphylaxis. Factors that control IgE production are therefore essential to the pathogenesis of these important afflictions. But a complete understanding of this topic is lacking, while new data have raised questions regarding the precise role of IgE in atopic disease. Evolving concepts of IgE production and elimination are likely to clarify the importance of IgE in health and disease.

Suggested Citation

  • David B. Corry & Farrah Kheradmand, 1999. "Induction and regulation of the IgE response," Nature, Nature, vol. 402(6760), pages 18-23, November.
    • Handle: RePEc:nat:nature:v:402:y:1999:i:6760:d:10.1038_35037014
    DOI: 10.1038/35037014
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    1. Lachlan P. Deimel & Lucile Moynié & Guoxuan Sun & Viliyana Lewis & Abigail Turner & Charles J. Buchanan & Sean A. Burnap & Mikhail Kutuzov & Carolin M. Kobras & Yana Demyanenko & Shabaz Mohammed & Mat, 2024. "Covalent penicillin-protein conjugates elicit anti-drug antibodies that are clonally and functionally restricted," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
    2. Olivia M. Man & Tamiris Azamor & Mary Catherine Cambou & Trevon L. Fuller & Tara Kerin & Sophia G. Paiola & Jessica S. Cranston & Thalia Mok & Rashmi Rao & Weiqiang Chen & Jae U. Jung & Viviana Fajard, 2024. "Respiratory distress in SARS-CoV-2 exposed uninfected neonates followed in the COVID Outcomes in Mother-Infant Pairs (COMP) Study," Nature Communications, Nature, vol. 15(1), pages 1-11, December.

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