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Coated-pit dynamics

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  • Jennifer Lippincott-Schwartz

    (the Cell Biology and Metabolism Branch, NICHD, National Institutes of Health)

Abstract

Many membrane proteins are taken up into the cell by the process of clathrin-mediated endocytosis — the proteins are pinched off in vesicles coated with the protein clathrin. A study using a fusion protein (green fluorescent protein combined with the clathrin light-chain) now indicates that formation of these coated pits may be coupled to events at the membrane skeleton, possibly through scaffold proteins.

Suggested Citation

  • Jennifer Lippincott-Schwartz, 1999. "Coated-pit dynamics," Nature, Nature, vol. 398(6730), pages 753-753, April.
  • Handle: RePEc:nat:nature:v:398:y:1999:i:6730:d:10.1038_19632
    DOI: 10.1038/19632
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