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Life and death of a signal peptide

Author

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  • Gunnar von Heijne

    (Arrhenius Laboratories, Stockholm University)

Abstract

The signal peptide is a small extension at one end of a newly synthesized protein chain. It directs the transport of that protein across membranes, and is then cleaved off by a signal peptidase. The structure of a bacterial signal peptidase is now reported, and it reveals features that tell us how this unusual enzyme works.

Suggested Citation

  • Gunnar von Heijne, 1998. "Life and death of a signal peptide," Nature, Nature, vol. 396(6707), pages 111-113, November.
    • Handle: RePEc:nat:nature:v:396:y:1998:i:6707:d:10.1038_24036
    DOI: 10.1038/24036
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