IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v392y1998i6676d10.1038_33276.html
   My bibliography  Save this article

Worlds in common through NF-κB

Author

Listed:
  • Cheryll Tickle

    (University College London)

Abstract

The regulator of gene transcription, NF-κB, was first identified in the B cells of the immune system. A further function for it is emerging through studies of the chick limb, and two new papers show that NF-κB is on the signalling pathway that specifies correct limb development — when its activity is blocked, the result is truncated limbs. This line of research is all the more intriguing because of close parallels with development in the fruitflyDrosophila, and because mutations in one of the signalling targets of NF-κB, a gene called Twist, result in a human condition characterized by limb anomalies.

Suggested Citation

  • Cheryll Tickle, 1998. "Worlds in common through NF-κB," Nature, Nature, vol. 392(6676), pages 547-548, April.
    • Handle: RePEc:nat:nature:v:392:y:1998:i:6676:d:10.1038_33276
    DOI: 10.1038/33276
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/33276
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/33276?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:392:y:1998:i:6676:d:10.1038_33276. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.