IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v391y1998i6668d10.1038_35504.html
   My bibliography  Save this article

Viral envelope fails to deliver?

Author

Listed:
  • Dani P. Bolognesi

    (Duke University Medical Center)

  • Thomas J. Matthews

    (Duke University Medical Center)

Abstract

Clinical trials of vaccines against the human immunodeficiency virus are underway, but initial results do not seem promising — at least for one type of vaccine. By injecting patients with a recombinant form of a viral envelope protein, gp120, the idea was to induce an antibody response that could fight subsequent infection with the virus. But in a trial of 18 people, all became infected with HIV-1 and, at the level of the immune system, those who had received the vaccine did not seem to deal with the infection any differently than unvaccinated patients.

Suggested Citation

  • Dani P. Bolognesi & Thomas J. Matthews, 1998. "Viral envelope fails to deliver?," Nature, Nature, vol. 391(6668), pages 638-639, February.
    • Handle: RePEc:nat:nature:v:391:y:1998:i:6668:d:10.1038_35504
    DOI: 10.1038/35504
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/35504
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/35504?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:391:y:1998:i:6668:d:10.1038_35504. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.