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Inositol lipid pathways turn turtle

Author

Listed:
  • Kath Hinchliffe

    (University of Cambridge)

  • Robin Irvine

    (University of Cambridge)

Abstract

Phospholipids are important components of cellular signalling pathways and of cell membranes. Two papers in this issue now suggest that phosphatidylinositol-4,5-bisphosphate, a key player in phospholipid synthesis, can be produced by an alternative pathway that involves an enzyme identified nearly a decade ago and a novel lipid substrate. Another newly discovered inositol lipid in this pathway, phosphatidylinositol-3,5-bisphosphate, appears to be involved in the response to osmotic stress in yeast and in mammalian cells.

Suggested Citation

  • Kath Hinchliffe & Robin Irvine, 1997. "Inositol lipid pathways turn turtle," Nature, Nature, vol. 390(6656), pages 123-124, November.
    • Handle: RePEc:nat:nature:v:390:y:1997:i:6656:d:10.1038_36458
    DOI: 10.1038/36458
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