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Homeotic transformation in Drosophila

Author

Listed:
  • B. Starling Emerald

    (Cytogenetics Laboratory, Banaras Hindu University)

  • J. K. Roy

    (Cytogenetics Laboratory, Banaras Hindu University)

Abstract

Fossil records indicate that insect wings are pleural appendages, primitively present on three thoracic and the nine abdominal segments as wings and winglets, respectively1. Homeotic proteins are generally considered to be the ontogenic switches governing the choice of developmental pathway of such appendages2. Here we provide examples of regulatory changes in developmental genes leading to a homeotic transformation in the ectopic wing tissue of prothoracic or metathoracic segments in Drosophila melanogaster, which lead to the development of wings rather than halteres.

Suggested Citation

  • B. Starling Emerald & J. K. Roy, 1997. "Homeotic transformation in Drosophila," Nature, Nature, vol. 389(6652), pages 684-684, October.
    • Handle: RePEc:nat:nature:v:389:y:1997:i:6652:d:10.1038_39500
    DOI: 10.1038/39500
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