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Neurodegeneration A silent channel opens its gates

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  • Peter H. Seeburg

    (Max Planck Institute for Medical Research)

Abstract

Many human neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease are caused by the death of specific populations of nerve cells. Using a strain of mutant mouse known aslurcher-- which has a peculiar gait caused by the loss of neurons in a brain structure that is important for motor coordination -- a new study has shown that cell death is due to a mutation in the δ2 subunit of the glutamate receptor.

Suggested Citation

  • Peter H. Seeburg, 1997. "Neurodegeneration A silent channel opens its gates," Nature, Nature, vol. 388(6644), pages 716-717, August.
    • Handle: RePEc:nat:nature:v:388:y:1997:i:6644:d:10.1038_41880
    DOI: 10.1038/41880
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