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The tinkerer's evolving tool-box

Author

Listed:
  • E. Richard Moxon

    (John Radcliffe Hospital)

  • David S. Thaler

    (Sackler Laboratory of Molecular Genetics and Informatics, The Rockefeller University)

Abstract

By knowing the mechanisms through which genetic variants are generated, we should gain a better understanding of evolution. Two new papers — one theoretical and one experimental — show that mutator alleles (which can lead to a huge increase in mutation rate) can speed up the rate at which bacteria adapt to a changing environment, even if these alleles remain at a low frequency.

Suggested Citation

  • E. Richard Moxon & David S. Thaler, 1997. "The tinkerer's evolving tool-box," Nature, Nature, vol. 387(6634), pages 659-662, June.
    • Handle: RePEc:nat:nature:v:387:y:1997:i:6634:d:10.1038_42607
    DOI: 10.1038/42607
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