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Overview of the yeast genome

Author

Listed:
  • H. W. Mewes

    (Max-Planck-Institut für Biochemie)

  • K. Albermann

    (Max-Planck-Institut für Biochemie)

  • M. Bähr

    (Max-Planck-Institut für Biochemie)

  • D. Frishman

    (Max-Planck-Institut für Biochemie)

  • A. Gleissner

    (Max-Planck-Institut für Biochemie)

  • J. Hani

    (Max-Planck-Institut für Biochemie)

  • K. Heumann

    (Max-Planck-Institut für Biochemie)

  • K. Kleine

    (Max-Planck-Institut für Biochemie)

  • A. Maierl

    (Max-Planck-Institut für Biochemie)

  • S. G. Oliver

    (University of Manchester Institute of Science And Technology (UMIST))

  • F. Pfeiffer

    (Max-Planck-Institut für Biochemie)

  • A. Zollner

    (Max-Planck-Institut für Biochemie)

Abstract

The collaboration of more than 600 scientists from over 100 laboratories to sequence the Saccharomyces cerevisiae genome was the largest decentralised experiment in modern molecular biology and resulted in a unique data resource representing the first complete set of genes from a eukaryotic organism. 12 million bases were sequenced in a truly international effort involving European, US, Canadian and Japanese laboratories. While the yeast genome represents only a small fraction of the information in today’s public sequence databases, the complete, ordered and non-redundant sequence provides an invaluable resource for the detailed analysis of cellular gene function and genome architecture. In terms of throughput, completeness and information content, yeast has always been the lead eukaryotic organism in genomics; it is still the largest genome to be completely sequenced.

Suggested Citation

  • H. W. Mewes & K. Albermann & M. Bähr & D. Frishman & A. Gleissner & J. Hani & K. Heumann & K. Kleine & A. Maierl & S. G. Oliver & F. Pfeiffer & A. Zollner, 1997. "Overview of the yeast genome," Nature, Nature, vol. 387(6632), pages 7-8, May.
  • Handle: RePEc:nat:nature:v:387:y:1997:i:6632:d:10.1038_387s007
    DOI: 10.1038/387s007
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