IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v9y2018i1d10.1038_s41467-018-07816-4.html
   My bibliography  Save this article

Concurrent influence of top-down and bottom-up inputs on correlated activity of Macaque extrastriate neurons

Author

Listed:
  • Yaser Merrikhi

    (Institute for Research in Fundamental Sciences (IPM))

  • Kelsey Clark

    (University of Utah)

  • Behrad Noudoost

    (University of Utah)

Abstract

Correlations between neurons can profoundly impact the information encoding capacity of a neural population. We studied how maintenance of visuospatial information affects correlated activity in visual areas by recording the activity of neurons in visual area MT of rhesus macaques during a spatial working memory task. Correlations between MT neurons depended upon the spatial overlap between neurons’ receptive fields. These correlations were influenced by the content of working memory, but the effect of a top-down memory signal differed in the presence or absence of bottom-up visual input. Neurons representing the same area of space showed increased correlations when remembering a location in their receptive fields in the absence of visual input, but decreased correlations in the presence of a visual stimulus. This set of results reveals the correlating nature of top-down signals influencing visual areas and uncovers how such a correlating signal, in interaction with bottom-up information, could enhance sensory representations.

Suggested Citation

  • Yaser Merrikhi & Kelsey Clark & Behrad Noudoost, 2018. "Concurrent influence of top-down and bottom-up inputs on correlated activity of Macaque extrastriate neurons," Nature Communications, Nature, vol. 9(1), pages 1-12, December.
    • Handle: RePEc:nat:natcom:v:9:y:2018:i:1:d:10.1038_s41467-018-07816-4
    DOI: 10.1038/s41467-018-07816-4
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-018-07816-4
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/s41467-018-07816-4?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Mehrabbeik, Mahtab & Shams-Ahmar, Mohammad & Levine, Alexandra T. & Jafari, Sajad & Merrikhi, Yaser, 2022. "Distinctive nonlinear dimensionality of neural spiking activity in extrastriate cortex during spatial working memory; a Higuchi fractal analysis," Chaos, Solitons & Fractals, Elsevier, vol. 158(C).

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:9:y:2018:i:1:d:10.1038_s41467-018-07816-4. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.