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Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk

Author

Listed:
  • Nicola Pirastu

    (Usher Institute of Population Health Sciences and Informatics, University of Edinburgh)

  • Peter K. Joshi

    (Usher Institute of Population Health Sciences and Informatics, University of Edinburgh)

  • Paul S. Vries

    (The University of Texas Health Science Center at Houston)

  • Marilyn C. Cornelis

    (Northwestern University Feinberg School of Medicine)

  • Paul M. McKeigue

    (University of Edinburgh)

  • NaNa Keum

    (Dongguk University
    Harvard T. H. Chan School of Public Health)

  • Nora Franceschini

    (University of North Carolina)

  • Marco Colombo

    (University of Edinburgh)

  • Edward L. Giovannucci

    (Harvard T. H. Chan School of Public Health
    Harvard T. H. Chan School of Public Health
    Brigham and Women’s Hospital and Harvard Medical School)

  • Athina Spiliopoulou

    (University of Edinburgh
    Pharmatics Ltd)

  • Lude Franke

    (University Medical Center)

  • Kari E. North

    (University of North Carolina)

  • Peter Kraft

    (Harvard T. H. Chan School of Public Health)

  • Alanna C. Morrison

    (The University of Texas Health Science Center at Houston)

  • Tõnu Esko

    (University of Tartu
    Broad Institute of Harvard and MIT)

  • James F. Wilson

    (Usher Institute of Population Health Sciences and Informatics, University of Edinburgh
    University of Edinburgh, Western General Hospital, Crewe Road)

Abstract

We have been alerted that in our recent Article the calculations used to transform the heritability from the observed scale to the liability scale did not take into account the individuals in category 2 of the baldness scale, who were removed in our original analysis. This led to an overestimation of the heritability on the liability scale, which should have been 0.62 instead of 0.94. Moreover, in the Title and in the Abstract, we report that we can explain 38% of the risk, while in fact that is the proportion of heritability explained by the loci we discovered. These errors do not substantially change the paper or its conclusions apart from the statement MBP is therefore probably one of the most heritable complex traits. Genome-wide significant associations and pathway analyses are not affected in any way and male-pattern baldness remains less genetically complex than other complex traits. We wish to thank Yap et al. for bringing this to our attention.

Suggested Citation

  • Nicola Pirastu & Peter K. Joshi & Paul S. Vries & Marilyn C. Cornelis & Paul M. McKeigue & NaNa Keum & Nora Franceschini & Marco Colombo & Edward L. Giovannucci & Athina Spiliopoulou & Lude Franke & K, 2018. "Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk," Nature Communications, Nature, vol. 9(1), pages 1-1, December.
  • Handle: RePEc:nat:natcom:v:9:y:2018:i:1:d:10.1038_s41467-018-04857-7
    DOI: 10.1038/s41467-018-04857-7
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